We DNA test our puppies for 164 health conditions, coefficient of inbreeding and physical traits using a company called Embark. Embark is a lab that is partnered with the Cornell University College of Veterinary Medicine and is operated by a highly skilled team of canine and veterinary geneticists.
Embark tests for most or all testable genetic health conditions in nearly every breed. They test all dogs on their entire marker set which allows them to work with breeders and breed clubs to discover the genetic mutations behind currently untestable diseases.
Ultimate peace of mind comes from testing for over 160 known genetic health conditions in 16 different areas:
Kidney and Bladder
Brain and Spinal Cord
COEFFICIENT OF INBREEDING (COI)
Coefficient of Inbreeding (COI) is a measure of how genetically similar a dog’s parents are. From a genetic point of view, this translates to what percentage of the genome is identical on both its maternal and paternal strands (also known as homozygosity).
By taking a genome-wide, SNP-based approach, Embark’s COI is far more accurate than pedigree-based COI calculations, which do not take into account genetic recombination or the relatedness of more distant ancestors, or limited marker panel approaches, which are often not fully representative of the genome.
Why does COI matter? As a measure of inbreeding, COI is another valuable piece of information that helps us to keep our breed healthy.
Things to note:
COI of an individual dog does not give you an idea of the COI of their ancestors. For example, an F1 Goldendoodle will have a COI of virtually zero because there will be minimal similarity between a Golden Retriever and a Poodle. However, the Golden Retriever parent and the Poodle parents themselves could have much higher COIs depending on how related their parents were.